11. Myopathy

[Thyrotoxic myopathy].

A variety of neuromuscular disorders has been described in adults in association with overactivity of the thyroid (Millikan and Haines, 1953; Ramsay, 1966; Engel, 1972). The most common of these disorders is a chronic myopathy, characterized by muscular atrophy and weakness involving predominantly proximal muscles (Adams and Rosman, 1971). The myopathic symptoms may precede the symptoms of thyr...

Metabolic myopathy.

RECENT years have witnessed a considerably increased interest in disorders of muscle, resulting in large measure from the advent of new investigative techniques. This has led both to the clarification of the nature of known disorders and to the definition of new syndromes. In this review, a brief survey is given of current knowledge concerning myopathic disorders arising from metabolic disturba...

Chloroquine myopathy.

Amyloid myopathy

Symptoms of primary systemic amyloidosis include neuropathy, myopathy, and cardiac or renal insufficiency; multiple organ systems are often involved. Amyloidosis can involve both the central nervous system and peripheral nerves. Amyloid myopathy is a rare manifestation of primary systemic amyloidosis. It is less well recognized that amyloid can directly infiltrate and weaken skeletal muscle. Li...

Diagnosis: Myopathy

by Edward C. Smith, MD, and Dwight D. Koeberl, MD, PhD The rheumatologist is frequently called upon to evaluate patients with complaints of myalgia, muscle cramping, and fatigue. Because these symptoms may be nonspecific and lack any clear temporal or anatomic pattern, their workup may entail costly and uninformative tests. When similar symptoms emerge during or following physical exertion, a m...